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The Future of Fentanyl and Other Synthetic Opioids
https://www.rand.org/pubs/research_reports/RR3117.html Comment; Lots of good, useful information in this Rand report regarding synthetic opioids, especially Fentanyl and the fact that the biggest factor to it's spread is not demand, but supply & the fact that once...
Intranasal Nystatin Therapy in Patients with Chronic Illness Associated with Mold and Mycotoxins
https://bc3-production-blobs-us-east-2.s3.us-east-2.amazonaws.com/64dd71fc-db33-11e9-8d32-a0369f740df5?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAJA4YU4LL6QTTS55A%2F20190924%2Fus-east-2%2Fs3%2Faws4_request&X-Amz-Date=20190924T155512Z&X-Amz-Expires=86400&X-Amz...
Mast Cells in Cardiovascular Disease: From Bench to Bedside
https://iseai.org/wp-content/uploads/2019/09/Mast-Cells-in-Cardiovascular-Disease-From-Bench-to-Bedside.pdf Comment; I hadn't realized the role of mast cells in the generation of foam cells and plaque. Fascinating! More to follow for certain! M. A. W. Hermans, J. E....
Can This Powerful Hormone be the Key to Treating Type 2 Diabetes & More?
https://www.jillcarnahan.com/2019/09/11/can-this-powerful-hormone-be-the-key-to-treating-type-2-diabetes-more/?utm_source=Flatiron+Functional+Medicine+Newsletter&utm_campaign=c5513215dd-EMAIL_CAMPAIGN_2017_10_06_COPY_01&utm_medium=email&utm_term=0_a07715eedd-c5513215dd-...
Psychosis in Borrelia burgdorferi infection – part I: epidemiology, pathogenesis, diagnosis and treatment of neuroborreliosis
http://www.psychiatriapolska.pl/_629_640_.html Comment; Poland is having problems with tick-borne neuropsychiatric illnesses as well. Is this a case of improved recognition of a long-ongoing problem or has virulence increased? It's a tough call at present; more to be...
An Acarological Risk Model Predicting the Density and Distribution of Host-Seeking Ixodes scapularis Nymphs in Minnesota
http://www.ajtmh.org/content/journals/10.4269/ajtmh.17-0539 Comment; Models are a good start, they require ongoing validation however. In the United States, Lyme disease, caused by infection with Borrelia burgdorferi sensu stricto or less commonly by the...
Amblyomma americanum (Acari: Ixodidae) Ticks Are Not Vectors of the Lyme Disease Agent, Borrelia burgdorferi (Spirocheatales: Spirochaetaceae): A Review of the Evidence
https://appwell.net/wp-admin/post-new.php Comment; Interesting finding that what we thought we knew about Lyme transmitting tick's isn't as we first believed--time to clarify our understanding of the vector/disease relationship among the Ixodidae. Ellen Y...
Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer’s Disease
https://www.ncbi.nlm.nih.gov/pubmed/26311426 Comment; Which came first, chicken, egg, Mitochondropathy or Neuroinflammation? A complex and probably interrelated problem! Wilkins HM, Swerdlow RH1. Author information 1University of Kansas School of Medicine, MS...
Fungal infection in neural tissue of patients with amyotrophic lateral sclerosis
https://drive.google.com/drive/u/1/folders/1zX2ieWLaUXsQOElqJn5aIqh06OJrCB7j Comment; Fungal & polymicrobial fungal infections in the motor cortex, medulla & spinal cord in ALS patients not present in controls. I've heard reports of various oragnisms DNA being...
Reciprocal regulation between taurine and glutamate response via Ca2+- dependent pathways in retinal third-order neurons
https://drive.google.com/drive/u/1/folders/1zX2ieWLaUXsQOElqJn5aIqh06OJrCB7j Comment; We now have clear evidence of Glutamatergic (neuroexcitatory/toxic neurotransmitter) activity being modulated, "throttled back" by Taurine. Taurine may be an effective "antidote" to...
Review: Taurine: A “very essential” amino acid
https://drive.google.com/drive/u/1/folders/1zX2ieWLaUXsQOElqJn5aIqh06OJrCB7j Comment; Taurine has so many roles and effects on the brain and elsewhere, unfortunately it doesn't cross the intact blood-brain barrier (BBB) well. It counteracts many of the things that...
Study Shows How Serotonin and a Popular Anti-depressant Affect the Gut’s Microbiota
https://beyond-paleo.com/2019/09/12/study-shows-how-serotonin-and-a-popular-anti-depressant-affect-the-guts-microbiota/ Comment; Interesting study showing that two species of gut microbe grow better with serotonin supplementation, impaired growth with fluoxetine and...
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