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Oligodendroglia are protected from antibody-mediated complement injury by normal immunoglobulins
https://drive.google.com/file/d/1O0Zsf_zalnHQGDtQkexgV13VifDBCNVD/view?usp=sharing Comment; Complement is known to be active in chronic inflammatory response syndrome (CIRS). Antibody-dependent complement damage was inhibited in a dose-dependent manner by IV Ig. So...
Oligodendroglia are protected from antibody-mediated complement injury by normal immunoglobulins ‘‘IV Ig’’
https://drive.google.com/file/d/1O0Zsf_zalnHQGDtQkexgV13VifDBCNVD/view?usp=sharing Comment; Many mechanisms of action of IV Immunoglobulins including penetration within the cell membrane and even the nucleus of diseased cells, regulation of the immune system in the...
Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis
https://drive.google.com/file/d/1OBEdBtnajvuB44DdTe3bB2KoVhVe68tE/view?usp=sharing Comment; Fas-FasL regulate the CD4 'helper' and CD8 'cytotoxic/killer' cells by inducing apoptosis--cell death. MS happens when this regulation goes awry.
Immunological evidence and regulatory potential for cell-penetrating antibodies in intravenous immunoglobulin
https://drive.google.com/file/d/1OCGMkr5OxSEvsM5HOBbLZvLvEMLL2h2n/view?usp=sharing Comment; Not only does IgG penetrate into cells, but in healthy cells, it gets into the cytoplasm, in diseased cells, to the nucleus; where the action is in terms of cellular control....
Maybe It’s Lyme What happens when illness becomes an identity?
https://www.thecut.com/2019/07/what-happens-when-lyme-disease-becomes-an-identity.html Comment; It is a problem, yet an understandable one. Few physicians are truly Lyme-literate, the infection is hard to diagnose with contradictory criteria from major organizations,...
The Emerging Science of BMAA; DO CYANOBACTERIA CONTRIBUTE TO NEURODEGENERATIVE DISEASE?
https://mail.google.com/mail/u/2/#inbox/FMfcgxwDqfLDcrXHnCWkRNzjHdDPgFTh?projector=1&messagePartId=0.1 Comment; β-methylamino-l- alanine (BMAA), a toxin produced by blue-green algae (cyanobacteria) mimics & replaces serine causing mis-folded proteins leading to...
Conditions that are helped by Low Dose Naltrexone (LDN)
https://www.ldnresearchtrust.org/conditions Comment; Pretty extensive list of conditions that LDN benefits. Cardiac (heart) diseases Chronic Pain Dermatologic (skin) diseases Ears, Nose, Sinus, Throat Endocrine diseases Gastrointestinal diseases Hematologic/blood...
How Low Dose Naltrexone Works
https://www.ldnresearchtrust.org/how-naltrexone-works Comment; We need more study on the dextro-naltrexone isomer which seems to have more immune system activity whereas the levo- isomer is more active in the CNS. Interesting effects from this dose--seems so...
Low Dose Naltrexone and chronic pain – Pradeep Chopra, MD
https://www.ldnresearchtrust.org/content/low-dose-naltrexone-and-chronic-pain-pradeep-chopra-md Comment; Excellent summary of the use of LDN and theory that it operates in the NMDA & Glutamate receptor systems in the CNS. Opioids (narcotics) have been used for...
Borrelia miyamotoi infection leads to cross-reactive antibodies to the C6 peptide in mice and men
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(19)30418-5/fulltext Comment; Ever more complexities in the diagnosis (much less management) of Lyme and Borrelial infections! No wonder it's so hard to diagnose and treat effectively!
Oxytocin; The Hormone of Healing & Hope
https://drive.google.com/file/d/1NlGc5FYy3qAB-5udix8RzoVmHNfvzW2m/view?usp=sharing Comment; A great review of some of the many benefits & uses for Oxytocin--a remarkable hormone that helps so many different conditions, unfortunately though, generally only...
How to manage opioid addiction in the workplace
https://qz.com/work/1680229/how-to-manage-opioid-addiction-in-the-workplace/ Comment; "Employers have a bigger influence than families on promoting recovery". That says it all. We'll do more to protect our income stream than worry about how our family members feel...
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