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Bacteria–Host Interactions in Multiple Sclerosis
https://www.frontiersin.org/articles/10.3389/fmicb.2018.02966/full Comment; Molecular biology is showing us so many potential connections and possible interactions to promote and/or inhibit infection--things we had no prior suspicion of. Fascinating! Koch's famous...
High frequency of systemic mycoplasmal infections in Gulf War veterans and civilians with Amyotrophic Lateral Sclerosis (ALS).
https://bc3-production-blobs-us-east-2.s3.us-east-2.amazonaws.com/b49f772e-ad63-11e9-9ab8-a0369f740db1?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAJA4YU4LL6QTTS55A%2F20190725%2Fus-east-2%2Fs3%2Faws4_request&X-Amz-Date=20190725T193109Z&X-Amz-Expires=86400&X-Amz...
Study finds increased cannabis use during pregnancy
https://www.drugabuse.gov/news-events/news-releases/2019/06/study-finds-increased-cannabis-use-during-pregnancy Comment; Worrisome! I'd love to see some longer-term studies that look at growth and development of the children exposed in-utero to see how it affects...
Tickbusters on the Lookout for Lyme
https://www.newyorker.com/magazine/2019/07/29/tickbusters-on-the-lookout-for-lyme Comment; Good to be on the lookout and maintain surveilance, interesting Re; the pharmacopia in tick saliva... They come bearing vials and tweezers, with their pant legs tucked into...
CDC Agrees to Add Disclaimer to Lyme Disease Case Definition
https://www.webwire.com/ViewPressRel.asp?aId=243971 Comment; This should have happened years ago. How many folks with Lyme have not been diagnosed because of the narrow criteria proposed for surveilance case definition--which is not the same as clinical medicine!?...
A First-in-Human Study of alpha1H in Patients With Non-muscle Invasive Bladder Cancer
https://clinicaltrials.gov/ct2/show/NCT03560479 Comment; Interesting idea, using Alpha1H/Oleic acid combination to change folding pattern/tertiary structure resulting in "broad" anti-neoplastic activity--more research needed!
Persistence of Babesia microti Infection in Humans
https://www.mdpi.com/2076-0817/8/3/102 Comment; Babesia can be an occult infection-hard to find, hard to treat, supresses the immune system. With those genetically susceptible to CIRS it compounds the already impaired/dysregulated immune system leading to worse...
Newby responds to Washington Post’s slam about BITTEN
https://www.lymedisease.org/newby-responds-wapo/ Comment; WaPo is hardly a paragon of virtue & accurate reporting of news and current events--more of an opinion piece (to which they're entitled as we all are), that, unfortunately portrays itself as accurate and...
Rhesus Brain Transcriptomic Landscape in an ex vivo Model of the Interaction of Live Borrelia Burgdorferi With Frontal Cortex Tissue Explants
https://www.frontiersin.org/articles/10.3389/fnins.2019.00651/full Comment; This study looks at what genes are turned on when frontal cortex neuron's of Rheuses monkeys are exposed to Borrelia-the cause of Lyme disease. As it turns out, thousands of genes are...
Airborne fungal fragments and allergenicity
https://academic.oup.com/mmy/article/44/Supplement_1/S245/1747243 Comment; Sub-micron sized particles can be detected with immunologic techniques to determine what compounds that make up these small particles are dangerous to us. We're gaining ground scientifically in...
Fungal Fragments in Moldy Houses: A Field Study in Homes in New Orleans and Southern Ohio
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2153459/ Comment; A common fragment of mold structural component is at higher levels than were previously thought in what is considered to be a "normal" building. We need to clearly define what is the "safe" level for mold...
The Generality of Post-Antimicrobial Treatment Persistence of Borrelia burgdorferi Strains N40 and B31 in Genetically Susceptible and Resistant Mouse Strains
https://iai.asm.org/content/early/2019/07/09/IAI.00442-19 Comment; Viable, non-cultivable persistence 18 months after antibiotic treatment in mice. Wow. We can't grow 'em in the lab, we' couldn't kill them, they still live in the host and cause harm. Not good! We need...
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