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LASERS HIGHLIGHT KETAMINE’S DEPRESSION-FIGHTING SECRETS
https://www.wired.com/story/lasers-highlight-ketamines-depression-fighting-secrets/ Comment; A very cool way to look at the functioning brain... Now we need to learn a bit more about how ketamine works and come up with new molecules that can safely improve depression...
Two bills would help Florida tackle addiction and overdose epidemic
https://www.tallahassee.com/story/opinion/2019/04/11/two-bills-would-help-florida-tackle-addiction-and-overdose-epidemic/3404795002/ Comment; I agree with the need for parity with other diseases covered by health insurance. I think we need more information regarding...
Mental health parity a requirement for insurance: Op-Ed
https://www.ctpost.com/opinion/article/Mental-health-parity-a-requirement-for-insurance-13762575.php#item-85307-tbla-4 Comment; The purpose of health insurance is to pay for expensive care. I understand that it's a competitive business & cost is a major factor....
Comparative evaluation of group-based mindfulness-based stress reduction and cognitive behavioural therapy for the treatment and management of chronic pain: A systematic review and network meta-analysis
https://ebmh.bmj.com/content/22/1/26 Comment; It's well-known and accepted that anxious & depressed patients hurt more. The limbic system in the brain manages emotions and is heavily involved in pain perception. CBT & Mindfulness makes sense as adjunctive...
Opioid Overdose in the Hospital Setting A Systematic Review
https://journals.lww.com/journaladdictionmedicine/Abstract/publishahead/Opioid_Overdose_in_the_Hospital_Setting__A.99358.aspx Comment; Definition isn't clear. How many physicians have treated post-surgical pain resulting in a patient sleeping most of the day. Is that...
Fear, Loathing and Fentanyl Exposure
https://www.nytimes.com/2019/04/04/opinion/fentanyl-opioids-exposure.html Comment; Great talk about safety of Fentanyl. OK, what about Carfentanil and the fact that street drugs are not labeled, regulated; one never knows what "that powder" actually is?! I disagree...
Stationary Phase Persister/Biofilm Microcolony of Borrelia burgdorferi Causes More Severe Disease in a Mouse Model of Lyme Arthritis: Implications for Understanding Persistence, Post-Treatment Lyme Disease Syndrome (PTLDS), and Treatment Failure
http://www.discoverymedicine.com/Jie-Feng/2019/03/persister-biofilm-microcolony-borrelia-burgdorferi-causes-severe-lyme-arthritis-in-mouse-model/ Comment; I like the proposed new way of considering the Lyme disease with new treatment recommendations that appear to be...
The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype
https://www.frontiersin.org/articles/10.3389/fmicb.2019.00690/full Comment; Epigenetics-control of gene regulation--where the "rubber meets the road". This is where it happens, figure out how to control the genes and maybe we can figure out how to get around the...
Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1
https://www.dovepress.com/precision-medicine-retrospective-chart-review-and-data-analysis-of-200-peer-reviewed-article-IJGM Comment; Using an anti-inflammatory antibiotic for a disease such as Lyme et al, difficult due to intracellular location & biofilm...
Laboratory Blood-Based Testing for Lyme Disease at a National Reference Laboratory
https://academic.oup.com/ajcp/advance-article-abstract/doi/10.1093/ajcp/aqz030/5461358?redirectedFrom=fulltext Comment; This begets the question; is the incidence increasing or are we just recognizing more of what's been present all along... Elizabeth...
ONLY A MINORITY OF CHILDREN WITH LYME DISEASE RECALL A TICK BITE
http://danielcameronmd.com/only-a-minority-of-children-with-lyme-disease-recall-a-tick-bite/ Comment; Unsuprising but a great reminder that we need to keep a high index of suspicion for testing even with a thorough medical history! by Daniel J. Cameron, MD, MPH The...
Borrelia and Chlamydia can form mixed biofilms in infected human skin tissues
https://akademiai.com/doi/10.1556/1886.2019.00003 Comment; Interesting that such indolent infectious agents can co-exist within lymphoid tissue in a symbiotic relationship within biofilms formed for mutual defense. Sapi E. Related information1Department of...
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