Citrulline boosts nitric oxide production in the body. Nitric oxide helps your arteries relax and work better, which improves blood flow throughout your body. This may be helpful for treating or preventing some diseases. There is some evidence to suggest the supplement could possibly help lower blood pressure in people with prehypertension. This is an early warning sign for high blood pressure. It means you have a slightly raised blood pressure reading of 120/80 to 139/89. Prehypertension raises your risk for high blood pressure and heart disease.
L-citrulline supplements may ease symptoms of mild-to-moderate erectile dysfunction (ED). Scientists say L-citrulline does not work as well as ED drugs such as Viagra. However, it appears to be a safe option. It should also be used very cautiously or, preferably avoided by those taking medications such as Viagra. Animal studies suggest L-citrulline might also help people with blood vessel problems such as slow wound healing due to diabetes. Other animal research says L-citrulline might improve muscle protein levels and prevent malnourishment in the elderly.
The animal research also suggests L-citrulline may help treat intestinal problems, including Short bowel syndrome, Celiac disease and Radiation-caused small bowel damage. Certain genetic disorders and health conditions such as liver disease may be helped by L-citrulline supplements. Early human studies done also hint that L-citrulline may be helpful for Parkinson’s disease and certain dementias. Some people also take L-citrulline to build muscles and improve athletic performance. But research shows it does not help well-trained athletes perform or exercise better.
Kidneys change L-citrulline into another amino acid called L-arginine and a chemical called nitric oxide. These compounds are important to your heart and blood vessel health. They may also boost your immune system.
