Functions

  • Necessary for >300 biochemical reactions
  • Conversion of carbohydrate & fat into energy
  • Synthesis of proteins & nucleic acids
  • Cell signaling
  • Structural role in bones & teeth
  • Needed to retain potassium

Deficiency Syndrome

  • Appetite loss (anorexia)
  • Weight loss
  • Nausea, vomiting
  • Fatty stool
  • Ataxia (loss of coordination)
  • Seizures
  • Irritability
  • Confusion
  • Tremors
  • Irregular heart rate

Toxicity

  • Drowsiness, CNS Depression, Coma
  • Muscle weakness, paralysis, decreased muscle reflexes
  • Respiratory failure
  • Low BP
  • Heart arrhythmias
  • Diarrhea if taken by mouth