New approach to drug development could give rise to cocaine treatment

https://www.addictionpro.com/article/medications/new-approach-drug-development-could-give-rise-cocaine-treatment?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+AddictionProfessionalMagazine+%28Addiction+Professional+Magazine%29

Gary A. Enos, Editor

At doses that by themselves would produce no effect, a combination of oxazepam and metyrapone (a cortisol synthesis inhibitor) was found in a study published in 2008 to reduce cocaine self-administration in rats. That research attracted the interest of investors and the establishment of Boston-based pharmaceutical company Embera NeuroTherapeutics, Inc.

Currently, we know of a few medications that can be used off-label to help with cocaine abuse;

• Vigabatrin
• Gabapentin
• Baclofen
• N-acetylcysteine
• Nocaine
• Disulfiram
• Modafinil

It will be nice to have other options, more effective options, this is an interesting study

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Dr. Raymond Oenbrink

Dr. Raymond Oenbrink DO is board certified by the American Osteopathic Board of Family Physicians (AOBFP) and the American Board of Addiction Medicine (ABAM). He specializes in complex and chronic illnesses such as Chronic Inflammatory Response Syndrome (CIRS).

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