https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2720587

Comment; It’s no surprise that vetrinary prescribing of opioids follow the patterns of human prescribing by physicians; pharmaceutical companies won’t miss a market!

Dana L. Clarke, VMD1Kenneth J. Drobatz, DVM, MSCE1Chloe Korzekwa2et alLewis S. Nelson, MD3Jeanmarie Perrone, MD4Author AffiliationsArticle InformationJAMA Netw Open. 2019;2(1):e186950. doi:10.1001/jamanetworkopen.2018.6950Key Points

Question  What kind of opioids and how many are prescribed by veterinarians?

Findings  In this cross-sectional inventory study of opioid prescribing by 134 veterinarians in a multidisciplinary acute care veterinary teaching hospital in Pennsylvania, a parallel trend of escalating opioid prescriptions and potency was found from 2007 through 2017. The substantial and increasing volume of opioids prescribed highlights analogous concerns about excessive opioid prescribing in humans.

Meaning  Veterinarians prescribe a substantial amount of opioids, so prescribing practices of veterinarians merit further evaluation to safeguard public health.Abstract

Importance  Veterinarians are a subset of opioid prescribers.

Objective  To assess the quantity and trends in prescribing and dispensing of several different opioids in the past 11 years in a large veterinary hospital in Philadelphia, Pennsylvania.

Design, Setting, and Participants  This cross-sectional study inventoried all opioid tablets and/or patches dispensed or prescribed by veterinarians practicing in a multispecialty academic veterinary teaching hospital in Philadelphia for small animals and species, such as rabbits, birds, and reptiles, from January 1, 2007, through December 31, 2017. Prescribing data were obtained from all veterinarians who wrote a prescription for opioids by reviewing detailed pharmacy records of controlled substances for the study period. Data included all opioids dispensed, or prescribed to animals (patients) undergoing evaluation at the center or being followed up as outpatients by the veterinarians in the hospital. Statewide veterinarian prescribing data were used for comparison. Data were analyzed from December 24, 2017, through May 15, 2018.

Main Outcomes and Measures  The trend in administration and prescribing of 4 specific opioid analgesics (codeine sulfate, hydrocodone bitartrate, and tramadol hydrochloride tablets as well as fentanyl citrate patch) during the 11-year study period. The individual opioids were converted to morphine milligram equivalents (MME) for comparison.

Results  The study included 134 veterinarians (70.9% women) with 366 468 patient visits. During the study period, the hospital veterinarians prescribed 105 183 689 tablets of tramadol, 97 547 tablets of hydrocodone, 38 939 tablets of codeine, and 3153 fentanyl patches to dogs (73.0%), cats (22.5%), and exotic animals (4.5%). Overall, MME use increased 41.2%, whereas visits increased by 12.8%. The comparison data for Pennsylvania revealed a predominance of hydrocodone use (688 340 tablets prescribed), although data were not available for comparison with tramadol because it is a Schedule IV drug.

Conclusions and Relevance  Results of this study suggest that the large, increasing volume of opioids prescribed at 1 veterinary teaching hospital highlights concerns parallel to those about excessive opioid prescribing in humans. The extent to which these data may represent similar volumes of prescriptions from the general veterinary practices and hospitals across the United States is suggested by the accompanying Pennsylvania state data. These findings highlight an opportunity to assess the risk of veterinarian opioid prescriptions to safeguard public health.

Dr. Raymond Oenbrink