Case report Sjögren’s syndrome and lymphadenopathy unraveling the diagnosis of Lyme disease

by | CIRS, Lyme Disease & Atypical Infections

https://www.termedia.pl/Sjogren-s-syndrome-and-lymphadenopathy-unraveling-the-diagnosis-of-Lyme-disease,18,35945,0,1.html

Comment; Typically, Lyme doesn’t present with swollen lymph nodes & Sjogren’s syndrome. This is a case that had a very happy outcome for the patient; instead of lymphoma, she has Lyme disease.

Svitlana Smiyan, Igor Galaychuk, Igor Zhulkevych, Volodymyr Nykolyuk, Roman Komorovsky, Sofiya Gusak, Ivan Bilozetsky

Reumatologia 2019; 57, 1: 59-62DOI: https://doi.org/10.5114/reum.2019.83242Online publish date: 2019/02/28View full textGet citation Lyme disease is a multisystem tick-borne transmissive disease with heterogeneous manifestations, frequently making the diagnosis difficult in clinical practice. Herein, we report a case of a 43-year-old female patient who presented with generalized lymphadenopathy requiring a further diagnostic evaluation towards lymphoma. The patient also had clinical signs of Sjögren’s syndrome. Lymph node excision with subsequent histological and immunohistochemical studies were performed. While light microscopy findings were suspicious for lymphoma, immunohistochemistry results were consistent with cortical and paracortical lymph node hyperplasia with no evidence of lymphoproliferative disorder. Further laboratory testing confirmed the presence of Lyme borreliosis. Effectiveness of the administered antibiotic therapy confirmed Borrelia burgdorferi infection. Interrelationships between Sjögren’s syndrome, lymphadenopathy and Lyme disease are discussed.

Dr. Raymond Oenbrink
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