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Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose A Randomized Clinical Trial

by Dr. Raymond Oenbrink | Uncategorized

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2755306 Comment; IM is better than IN as a route for emergency delivery of Naloxone to reverse opioid overdose. Paul Dietze, PhD1,2; Marianne Jauncey, MPH...

A scoping review of post opioid-overdose interventions

by Dr. Raymond Oenbrink | Addiction

https://www.sciencedirect.com/science/article/pii/S0091743519302890?via%3Dihub Comment; Post-overdose care should include drug use disorder help as it is the time frame most likely to be effective in getting a user who nearly died to re-assess their life and what they...

How Low Dose Naltrexone Works

by Dr. Raymond Oenbrink | CIRS, Functional & Integrative Medicine, ISEAI

https://www.ldnresearchtrust.org/how-naltrexone-works Comment; We need more study on the dextro-naltrexone isomer which seems to have more immune system activity whereas the levo- isomer is more active in the CNS. Interesting effects from this dose–seems so...

Low Dose Naltrexone and chronic pain – Pradeep Chopra, MD

by Dr. Raymond Oenbrink | CIRS, Functional & Integrative Medicine, ISEAI

https://www.ldnresearchtrust.org/content/low-dose-naltrexone-and-chronic-pain-pradeep-chopra-md Comment; Excellent summary of the use of LDN and theory that it operates in the NMDA & Glutamate receptor systems in the CNS. Opioids (narcotics) have been used for...

FDA clears the way to increase access and lower cost of life-saving opioid overdose treatment drug

by Dr. Raymond Oenbrink | Addiction

https://www.cnbc.com/2019/01/16/fda-wants-pharma-to-bring-opioid-antidote-naloxone-over-the-counter.html Comment; I like the idea of making it an OTC drug, to much profiteering for to long with this particular life-saver! Big pharma should be ashamed! Naloxone is used...

Here Are California’s New Laws To Address The State’s Opioid Crisis

by Dr. Raymond Oenbrink | Addiction

http://www.capradio.org/articles/2019/01/16/here-are-californias-new-laws-to-address-the-states-opioid-crisis/ Comment; I like that CA is working to help reduce opioid prescribing and putting more restrictions on doctors (ugh!), but they’re forgetting that most...

Anxiety, Depression, and Insomnia Among Adults With Opioid Dependence Treated With Extended-Release Naltrexone vs Buprenorphine-Naloxone A Randomized Clinical Trial and Follow-up Study

by Dr. Raymond Oenbrink | Addiction

https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2718627 Comment; Long term treatment with naltrexone seems to work as well for anxiety, depression & insomnia as combination buprenorphine/naloxone...

Opioids fueled a doubling of suicides and overdoses in the US

by Dr. Raymond Oenbrink | Addiction

https://www.sciencedaily.com/releases/2019/01/190107110837.htm Comment; Since 2000 there’s been a dramatic increase in both overdose & suicide, most of the overdose deaths & suicides involve opioids. It’s hard to determine suicide vs. accidental...

Medication Assisted Treatment for Opioid Use Disorders is the Standard of Care

by Dr. Raymond Oenbrink | Addiction

Medication Assisted Treatment for Opioid Use Disorders is the Standard of Care Comment; This has been known for some time by those of us “in the trenches”, good to see official recognition finally occuring! Medication Assisted Treatment for Opioid Use...

Naloxone still stable months after expiration date, research says

by Dr. Raymond Oenbrink | Addiction

https://www.cnn.com/2018/11/06/health/naloxone-expiration-date-potency-study/index.html Comment; Clearly we can save money and need more research on long-term stability of drugs, the process must be streamlined with the FDA too. By Naomi Thomas, CNN (CNN)Two common...

The costs of heroin and naloxone: a tragic snapshot of the opioid crisis

by Dr. Raymond Oenbrink | Addiction

The costs of heroin and naloxone: a tragic snapshot of the opioid crisis Comment; What a GREAT solution to the exorbitant cost of Naloxone! By MICHAEL HUFFORD and DONALD S. BURKE Lethally potent street drugs like heroin are increasingly affordable and available, while...

Dan Bigg remembered as ‘revolutionary’ for approach to heroin crisis, pioneered life-saving naloxone, needle handouts

by Dr. Raymond Oenbrink | Addiction

http://www.chicagotribune.com/news/local/breaking/ct-met-dan-bigg-heroin-obituary-20180821-story.html John Keilman Dan Bigg and Petra Hranova of the Chicago Recovery Alliance chat with an addict outside the organization’s van. The van is loaded with clean...
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